Parkinson’s disease

Parkinson's disease

Parkinson’s disease is the most developing and evolving neurodegenerative disorder that affects the motion of body. Early diagnosis for this disease is very important to control the signs and indications. However, like Alzheimer, there is no proper treatment is known for this disorder. From the routine changes to the motion effects, we will explain deeply in order to known the onset of Parkinson. Also we will shed light on the significance of medical interventions and assistance.

Understanding the Parkinson through Causes

It is a complex disease that affects movements, causes tremors, stiffness and difficulty in coordination. While the other causes are still in search, the identified several factors are here;

1. Neurotransmitter imbalance

The degeneration of neurons occurs in brain which are producing dopamine. Dopamine is a neurotransmitter that performs the movements. The dopamine forming cells become loss in the brain and condition is known as substantia nigral. This condition leads to lack of dopamine and affects the motion system.

2. Genetic Factors

Many cases of Parkinson’s disease are appeared sue to the genetic factors. This shows a major marker of this disorder. Alterations in some genes lead to increased cause of Parkinson’s disease. These genes are LRRK2, PARK2 and PINK1. However, only this condition will not show the confirmation of disorder.

3. Environmental Aspects

Some environmental agents may lead to the development of this mental disorder. People working in farming or agriculture, highly expose to pesticides, herbicides and other chemicals more susceptible to adopt Parkinson. While living in rural areas, well consumption of water and exposure to toxic agents increases the risk.

4. Age and sex

Age also play function in posing the diseases. Most people suffer from Parkinson are above sixty. The severity depends on the age difference, men are more susceptible than women but the discussion is still unclear.

5. Severe inflammation and Stress

These two are the major triggers for the induction of Parkinson’s disease. Acute inflammation and stress in brain cells is dangerous. These can damage the neurons and the regions of brain.

Parkinson's disease
Parkinson’s disease

Key Indications of Mental disorder

Early diagnosis is important to prevent from the critical conditions. Most of the symptoms are related with the movements while some other signs are also prominent. Early warning indications of this disease are here;

1. Convulsions

One of the important and visible symptoms of Parkinson is resting fits or twitch. The convulsions start from hands, fingers and feet. These are mostly seen in resting conditions and starts from to and fro movements.

2. Slow motions

In early stages, patient will feel reduction in motion or slow movements of body. This state is known as bradykinesia, affect the daily activities and perform tasks slowly.

3. Muscle stiffness due to Parkinson’s disease

The muscles become stiff and rigid and causes difficulty for patient to move freely and act flexibly. It can affect most importantly arms, neck and shoulders.

4. Posture Imbalance

Person feels complexity or challenging to maintain the body posture while standing or walking. This is the most common feature of Parkinson’s disease and the patient become still in his position.

5.  Decrease Arm movements

The person’s arm rotates and move naturally as a swing but suffering with this disorder causes the reduction of arm swing. This symptom combines with other indications and alter the body position.

6. Lack of facial expression

In Parkinson, the patient facial expression become masked and will unable to show expression and response. There will be no facial expressions.

7. Sleep Imbalance

Sleep disturbances, restlessness and early awakening are associated with Parkinson. These issues if not noticeable and go prolong will affect the body movements.

8. Difficulty in speech

The patient feels difficulty in speech or the voice becomes softer. These are the early indications of Parkinson’s disease. Sometimes the person feels challenging during pronunciation and articulation.

Curing the Parkinson’s

Treatment of Parkinson is still dynamic and recent researches and development strives for the advanced therapies. Here is an overview of emerging treatments;

1. Medications

The initial step to control theParkinson’s disease is medications and this includes L-dopamine known as Levodopa. This drug will maintain the body postures and movements by reducing the levels of dopamine in brain.

2. Deep Brain Stimulation

It is a surgical procedure in which electrodes insert into the specific regions of brain. These electrodes will connect to the pulse generator. The need for the medications will greatly reduce.

3. Therapies

These include the physical therapies to improve the body motions. Routine exercise will relax the muscles and shows flexibility. In addition of this, speech therapies will also aid in improving speech and communications.

4. Emerging therapies

These include different types of therapies such as gene therapy to replace the defective gene with the right one. Neurotherapies will able to improve the neurons and immune response. In stem-cell therapies, the dopamine producing neurons will replace to minimize the symptoms.

Diagnosing Parkinson’s Disorder

There are many ways to diagnose this disorder. Some of the methods include;

  • Clinical Assessment
  • Medical history
  • Physical examination
  • Blood test
  • DaTscan Imaging
  • Medication Results
  • Neurological examination
  • Brain imaging
  • Monitoring the Symptoms

Conclusion

Diagnosing Parkinson’s disease is not easy and requires several techniques to diagnose. Once it diagnosed, medications and therapies will provide to cure. If it cures at early stages, the patient will become successful returning towards the normal life. If a person feels any sign for this disease, seek immediate medical guidance to avoid complications.

Parkinson's disease

FAQS

1. Is Parkinson’s disease curable?

Proper treatment is not discovered yet but can be controlled through various ways.

2. Is there any surgical treatment for Parkinson?

Yes, insertion of electrodes in place of damage neurons is a surgical treatment for this purpose.

3. What are the symptoms of Parkinson’s disease?

These include muscles stiffness, loss of motion, balance and speech, convulsions.

4. Does loss of memory takes place in Parkinson’s?

Loss of memory and brain functioning sometimes develop in this disease.

5. How long can a person live with Parkinson’s?

A person can live long with Parkinson’s disease if proper medications will provide.

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